产品货号：
Z32937
中文名称：
AIF/AIFM1抗体
英文名称：
Anti-AIF/AIFM1 Antibody (Clone#2I5)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-AIF/AIFM1 Antibody (Clone#2I5) |
| 指标别名 | AIF;AIFM1;Mitochondrion Marker;PDCD8 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,IF,ICC/IF,FCM |
| 基因名称 | AIFM1 |
| 克隆号 | 2I5 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human AIF(582-613aa FNRMPIARKIIKDGEQHEDLNEVAKLFNIHED),identical to the related mouse and rat sequences. |
| 实际分子量 | 67KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Apoptosis-inducing factor 1,mitochondrial,also known as AIF or PDCD8 is a protein that in humans is encoded by the AIFM1 gene.AIFM1 gene is mapped to Xq26.1 based on an alignment of the AIFM1 sequence with the genomic sequence.This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells,and it is found in the mitochondrial intermembrane space in healthy cells.Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation.In addition,this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9.Mutations in this gene cause combined oxidative phosphorylation deficiency 6,which results in a severe mitochondrial encephalomyopathy.A related pseudogene has been identified on chromosome 10. |
| Uniprot ID | O95831 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1866) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | AIFM1 |
| 蛋白名全称 | Apoptosis-inducing factor 1,mitochondrial |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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